Objective. Students will assign CPT codes from the Radiology, Pathology/Laboratory, and Medicine sections, applying section-specific guidelines including professional and technical component rules for radiology.
This lesson, its worked examples and its practice questions has not yet been verified by a licensed clinician in the field or by a certification or approval body. It is a study draft and may contain errors. Do not use it to make decisions about any patient or medication. Always follow your instructor, your supervising professional, and current official references and regulations.
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The CPT manual organizes procedure codes into six sections. Three of those sections—Radiology (70010–79999), Pathology/Laboratory (80047–89398), and Medicine (90281–99199 and 99500–99607)—cover a wide range of diagnostic and therapeutic services. Each section begins with its own set of guidelines. Reading those guidelines before you code is not optional; it is the foundation of accurate coding.
Some radiology codes describe a complete study, which images all required anatomic elements as defined by CPT. A limited study covers fewer elements—for example, a limited ultrasound of the abdomen images only selected organs rather than all abdominal structures. The CPT code you choose must match the scope of the study actually performed and documented. Never code a complete study when the report describes a limited one, because overcoding is a compliance violation.
Many radiology procedures have two distinct parts:
When one entity provides both parts—for example, a free-standing imaging center that owns the equipment and employs its own radiologist—the global code (no modifier) is reported. When the parts are split between two entities, each reports only its portion:
Example: A hospital owns the MRI scanner. A radiologist who is in private practice (not a hospital employee) reads the scan and sends a written report. The hospital bills the global code with modifier -TC; the radiologist bills the same code with modifier -26.
Certain interventional and fluoroscopic radiology codes include supervision and interpretation (S&I) language in their descriptors. These codes capture the radiologist's role when a surgeon or other physician performs the primary procedure. Do not confuse S&I codes with stand-alone diagnostic imaging codes—read the full descriptor carefully.
A qualitative test reports whether a substance is present or absent (positive/negative). A quantitative test measures the amount of a substance. CPT often provides separate codes for these two types of testing, and they are not interchangeable. Always check the order and the report to confirm which type of result was produced.
CPT defines laboratory panels (e.g., a basic metabolic panel) by listing the specific tests that must all be performed for the panel code to apply. If fewer tests are done, code each individual test separately. If more tests are added beyond the panel definition, add those tests as individual codes alongside the panel code. Do not bundle tests into a panel code unless every test in the panel definition was performed.
Surgical pathology codes are assigned based on the level of physician work involved in examining tissue, ranging from gross examination only up to complex microscopic examination. The operative or pathology report must support the level billed.
The Medicine section is a catch-all for services not captured elsewhere: immunizations, infusions, ophthalmology exams, psychiatric services, physical medicine and rehabilitation, dialysis, and many others. Each subsection carries its own guidelines—always read the subsection introduction.
Immunization coding requires two codes: one for the vaccine product itself (the supply) and one for the administration. If a physician or qualified health professional counsels the patient about the vaccine, an additional counseling code may apply. Age and route of administration affect which administration code is correct.
The Medicine section contains many add-on codes (marked with a + symbol), which are always reported alongside a primary code and never alone. Pay attention to instructional notes such as "Do not report X with Y"—these notes prevent unbundling and duplicate billing, which are audit triggers.
As a coder, you do not diagnose patients or interpret clinical findings. If a radiology report is unclear—for example, if you cannot determine from the documentation whether a study was complete or limited—query the provider rather than guessing. Upcoding (billing a higher-intensity service than was performed) and downcoding both carry legal and financial consequences, but inaccurate coding can also distort patient records and indirectly affect care decisions. Protect patients by coding only what is documented.
Answer each question, then check it. Nothing is recorded; this is your own practice.
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